Figure 4. The hearts derived from adult-ATF3 expressing mice display a higher level of inflammatory response.

mRNA derived from ventricles of wild-type and ATF3 transgenic, as described in Figure 2C, was analyzed for the indicated inflammatory markers A. IL-6 B. F4/80 C. CD68. The results represent the mean expression relative to GAPDH of the indicated number of animals (n). Asterisks (*) indicate a P value <0.05 of a one-tailed t-test compared with wild-type mice.