Table 2.

Complete responses in tumor-bearing mice treated with rituximab with or without IL-18

Rituximab dose (mg/kg)	Number of mice with complete response/total number of mice treated per group
	No IL-18	IL-18 4 mg/kg
0.5	0/6	2/6
1	2/6	4/6
2	2/6	5/6

SCID mice (n = 6 per group) were injected with Ramos cells as described in Materials and Methods and given daily s.c. injections of recombinant murine IL-18 4 mg/kg or vehicle (“No IL-18”) as indicated together with twice weekly i.v. infusions of rituximab in doses of 0.5, 1, or 2 mg/kg as indicated