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. Author manuscript; available in PMC: 2013 Jul 10.
Published in final edited form as: Hepatology. 2009 Dec;50(6):1738–1749. doi: 10.1002/hep.23211

Figure 2.

Figure 2

Distribution of Ishak fibrosis stages at each biopsy among 535 patients used for morphometric analyses, showing an increasing proportion of patients with stage 6 cirrhosis (p<0.0001). Panels show the three randomization strata with lead-in nonresponders (n=346) in upper left, breakthrough/relapse (n=78) in upper right, express (n=111) in lower left and the total cohort (n=535) in lower right. There were no significant differences among the three strata at baseline. All three strata showed a significant increase in cirrhosis, but there were significantly fewer breakthrough/relapse patients with advanced stages at biopsy 2 (p=0.01) and biopsy 3 (p=0.004) than in the other two strata.