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. Author manuscript; available in PMC: 2013 Jul 10.
Published in final edited form as: Hepatology. 2009 Dec;50(6):1738–1749. doi: 10.1002/hep.23211

Table 3.

Changes in Ishak Fibrosis Scores over the course of the HALT-C Trial for the 535 patients used in the morphometric analyses. Three were missing biopsy 2 and two were missing biopsy 3. The score was considered improved if it decreased by one or more stage and worsened if it decreased by one or more stage.

n Improved Same Worsened
Baseline to Biopsy 2 532 30% 43% 27%
 IFN treated 261 31% 40% 29%
 Control 271 30% 44% 26%
Month 24 to Biopsy 3 531 26% 41% 33%
 IFN treated 261 28% 40% 32%
 Control 270 24% 42% 34%
Baseline to Biopsy 3 533 32% 34% 34%
 IFN treated 262 33% 34% 33%
 Control 271 31% 34% 35%