FIGURE 2.

Structure model for 22F6 light chain. A, side chains having the potential to form serine protease-like triads (Asp¹ (or Asp³⁴), Ser^27a, and His^27d) are shown. Asp, His, and Ser are colored red, blue, and green, respectively. The distance between Cα of His^27d and Ser^27a is 8.26 Å, which is close to the Cα distance (8.42 Å) between them in a catalytic triad of trypsin. B, Tyr³² is visualized. The residue is situated between Asp³⁴ and His^27d and may be concerned with the nuclease activity. Models for the light chain were visualized using WebLab ViewerLite (Accelrys Inc., San Diego, CA).