Table 1.
Results of population analysis profile (PAP) of selected carbapenem-resistant Acinetobacter baumannii isolates
| Strain | PFGE group | MIC (mg/L) | Highest concentration where growth occurred in population analysis (mg/L) | Frequency of appearance of subpopulations (PAP) | MIC after 4 days daily passages in drug-free medium (mg/L) | MIC after 75 days storage (mg/L) |
|---|---|---|---|---|---|---|
|
1 |
A |
≤ 0.125 |
1 |
6.6 × 10-5 |
1 |
≤ 0.125 |
|
2 |
A |
≤ 0.125 |
2 |
6 × 10-5 |
2 |
≤ 0.125 |
|
3 |
A |
0.25 |
NG |
NA |
NA |
NA |
|
4 |
A |
≤ 0.125 |
1 |
1 × 10-7 |
1 |
NP |
|
5 |
A |
0.25 |
1 |
5 × 10-5 |
1 |
NP |
|
6 |
A |
0.25 |
1 |
1.5 × 10-6 |
1 |
NP |
|
7 |
B |
≤ 0.125 |
0.5 |
5 × 10-4 |
0.5 |
≤ 0.125 |
|
8 |
B |
0.25 |
1 |
2.5 × 10-7 |
1 |
0.25 |
|
9 |
B |
≤ 0.125 |
0.5 |
1 × 10-6 |
0.5 |
NP |
|
10 |
C |
≤ 0.125 |
1 |
1.2 × 10-5 |
1 |
≤ 0.125 |
|
11 |
C |
1 |
1 |
NA |
1 |
1 |
|
12 |
C |
≤ 0.125 |
1 |
7.1 × 10-5 |
1 |
NP |
|
13 |
D |
≤ 0.125 |
1 |
1.3 × 10-6 |
1 |
NP |
|
14 |
D |
≤ 0.125 |
1 |
3.3 × 10-6 |
1 |
NP |
|
15 |
E |
0.25 |
1 |
1 × 10-6 |
1 |
NP |
|
16 |
F |
0.5 |
2 |
8.3 × 10-5 |
2 |
1 |
|
17 |
F |
≤ 0.125 |
1 |
1 × 10-6 |
1 |
≤ 0.125 |
|
18 |
G |
0.25 |
1 |
7.5 × 10-5 |
1 |
0.25 |
|
19 |
H |
0.25 |
1 |
3.3 × 10-4 |
1 |
0.25 |
|
20 |
I |
0.25 |
2 |
3.3 × 10-5 |
2 |
1 |
|
21 |
I |
0.5 |
1 |
3 × 10-6 |
1 |
1 |
|
22 |
J |
0.25 |
1 |
1.4 × 10-4 |
1 |
0.25 |
|
23 |
K |
0.25 |
NG |
NA |
NA |
NA |
|
24 |
L |
≤ 0.125 |
0.5 |
1.5 × 10-6 |
0.5 |
≤ 0.125 |
|
25 |
L |
≤ 0.125 |
1 |
4 × 10-4 |
1 |
NP |
|
26 |
M |
≤ 0.125 |
1 |
6.2 × 10-4 |
1 |
≤ 0.125 |
|
27 |
N |
0.5 |
2 |
6.6 × 10-5 |
2 |
1 |
|
28 |
N |
≤ 0.125 |
0.5 |
1.5 × 10-5 |
0.5 |
NP |
| 29 | O | ≤ 0.125 | 1 | 5 × 10-5 | 0.5 | 0.5 |
PAPs population analysis profiles, NA not applicable, NG no growth, NP not performed.