Table 1.
|
Female |
Male |
Male vs. Female |
|||||
---|---|---|---|---|---|---|---|---|
Cohort (years) |
C1 |
C2 |
C1 vs. C2 |
C1 |
C2 |
C1 vs. C2 |
C1 |
C2 |
38-46 | 54-62 | p | 38-46 | 54-62 | p | p | p | |
N |
258 |
153 |
|
93 |
47 |
|
|
|
Age (yrs) |
|
|
|
|
|
|
0.32 |
0.29 |
mean |
42.36 |
57.97 |
|
42.04 |
57.51 |
|
|
|
std. dev |
2.66 |
2.47 |
|
2.56 |
2.66 |
|
|
|
Race (% white)+ |
95.2 |
95.4 |
1 |
95.7 |
93.6 |
0.687 |
1 |
0.703 |
Ethnicity (% hispanic)* |
3.6 |
0.7 |
0.098 |
1.1 |
0 |
1 |
0.301 |
1 |
Current course type (%) |
|
|
<0.0001 |
|
|
0.0031 |
0.0011 |
0.0097 |
Relapsing (RRMS, CIS) |
96.5 |
77 |
|
86 |
72.3 |
|
|
|
SPMS |
2.4 |
15.7 |
|
10.8 |
6.4 |
|
|
|
PPMS |
1.2 |
6.5 |
|
3.2 |
21.3 |
|
1.2 |
6.5 |
Disease duration (yrs) |
|
|
<0.0001 |
|
|
0.01 |
0.71 |
0.01 |
Mean |
9.93 |
16.76 |
|
9.68 |
13.15 |
|
|
|
std. dev. |
6.02 |
9.47 |
|
5.66 |
8.45 |
|
|
|
Age at disease onset (yrs) |
32.42 (6.27) |
41.21 (9.65) |
<0.0001 |
32.37 (5.99) |
44.36 (9.24) |
<0.0001 |
0.94 |
0.05 |
RRMS, CIS Mean (SD) |
32.39 (6.33) |
41.32 (9.76) |
<0.0001 |
32.94 (5.72) |
44.35 (8.75) |
<.00001 |
0.49 |
0.105 |
SPMS Mean (SD) |
31.83 (4.17) |
37.71 (8.65) |
0.120 |
27.90 (5.78) |
38.67(10.41) |
0.036 |
0.169 |
0.860 |
PPMS Mean (SD) | 36.00 (4.36) | 46.20 (8.18) | 0.067 | 32.00 (9.54) | 46.10 (10.87) | 0.069 | 0.545 | 0.982 |
+8 missing and did not contribute to the analyses *9 missing and did not contribute to the analysis.