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. Author manuscript; available in PMC: 2013 Oct 1.
Published in final edited form as: Chronobiol Int. 2012 Aug 28;29(8):965–981. doi: 10.3109/07420528.2012.707264

FIGURE 2.

FIGURE 2

The behavioral effects of daytime RF under DD are altered in the absence of Dexras1. A–F, Representative double-plotted actograms of wheel-running activity of (A–C) WT and (D–F) dexras1−/− mice subjected to RF for six consecutive days under DD, between ZT 6 and ZT 11 (relative to the previous 12L:12D cycle). Subsequently, mice were returned to ad libitum (AL) feeding conditions and maintained in DD for an additional 2 wks. Areas shaded in gray indicate periods of light. Boxed regions indicate periods of food availability. Red lines denote regression lines fitted to daily activity onsets. LD1-AL, ad libitum feeding under the first 12L:12D schedule. DD1-AL = ad libitum feeding under the first DD schedule; LD2-AL = ad libitum feeding under the second 12L:12D schedule; DD2-RF = restricted feeding under the second DD schedule; DD2-AL = return to ad libitum feeding under the second DD schedule.