TABLE 3.
Statistical analysis of the circadian period of WT and dexras1−/− mice before and after late-night/early-morning RF under DD (Experiment 5).
RF-naíve* | WT (n = 7) | dexras1−/− (n = 7) | F value | p value |
---|---|---|---|---|
Period in week 1 of DD (τ1) [h] | 23.76 ± .01 | 23.67 ± .10 | F(1,13) = .7 | .43 |
Period in week 3 of DD (τ3) [h] | 23.78 ± .01 | 23.71 ± .12 | F(1,13) = .4 | .56 |
Δτ1 (τ3 − τ1) [h] | .03 ± .01 | .04 ± .04 | F(1,13)= .1 | .78 |
Period in week 5 of DD (τ5) [h] | 23.77 ± .02 | 23.71 ± .08 | F(1,13)= .1 | .79 |
Δτ2 (τ5 − τ1) [h] | .01 ± .01 | .08 ± .03 | F(1,13) = 3.2 | .10 |
| ||||
Night-time RF | WT (n = 6) | dexras1−/− (n = 6) | F value | p value |
| ||||
Period before RF (τpre) [h] | 23.66 ± .07 | 23.76 ± .10 | F(1,10)= .6 | .47 |
Period in week 2 post-RF (τpo1) [h] | 23.62 ± .04 | 23.95 ± .08 | F(1,10) = 12.7 | 5.1e-3 |
Δτ3 (τpo1 − τpre) [h] | −.04 ± .06 | .19 ± .04 | F(1,10) = 8.8 | .01 |
Period in week 4 post-RF (τpo2) [h] | 23.63 ± .05 | 24.14 ± .11 | F(1,10) = 16.6 | 2.2e-3 |
Δτ4 (τpo2 − τpre) [h] | −.02 ± .06 | .38 ± .07 | F(1,10) = 19.0 | 1.4e-3 |
Data are mean ± SEM.
A separate cohort of age-matched mice was maintained on ad libitum feeding under DD for 5 weeks for τ measurements.