Table 3.
Results of left and right ventricular (LV, RV) functional analysis performed by the two CMR sequences, self-gated FLASH and self-gated UTE as well as by echocardiography
| Echocardio-graphy§ | CMR Self-gated cine FLASH § | CMR Self-gated cine UTE § | p-values FLASH-UTE/FLASH-Ultrasound§ | |
|---|---|---|---|---|
|
LV morphology and function | ||||
| Mass [mg] |
91 ± 11 |
83.7 ± 5.8 |
83.6 ± 3.0 |
0.98/0.20 |
| Stroke volume (SV) [μl] |
35.0 ± 5.4 |
32.3 ± 6.9 |
32.3 ± 6.5 |
0.99/0.47 |
| Ejection fraction (EF) [%] |
54.7 ± 4.8 |
72.2 ± 3.2 |
71.8 ± 2.2 |
0.78/0.000022 |
| Cardiac output (CO) [ml/min] |
16.6 ± 3.2 |
15.6 ± 3.8 |
15.6 ± 3.8 |
0.99/0.63 |
|
RV morphology and function | ||||
| Mass [mg] |
- |
15.0 ± 4 |
19.3 ± 3.7 |
0.10 |
| Stroke volume (SV) [μl] |
31.7 ±7.5 (Doppler) |
22.9 ± 3.5 |
22.6 ± 3.9 |
0.89/0.026 |
| Ejection fraction (EF) [%] |
- |
72.4 ± 6.1 |
69.6 ± 3.2 |
0.34 |
| Cardiac output (CO) [ml/min] | 13.2 ± 3.2 (Doppler) | 11.0 ± 2.2 | 10.9 ± 2.1 | 0.89/0.20 |
§Values are given as mean ± standard deviation values averaged over six healthy C57BL/6 mice.