Figure 3. Cyclin B1 expression in normal, fibroadenoma and malignant breast tissues.

(A) Cyclin B1 gene expression across all tissue types. Cyclin B1 gene expression was significantly elevated in breast cancer (Mean(SEM) 2.52 (0.10) Log₁₀ RQ) compared to benign (2.15 (0.11) Log₁₀ RQ, p<0.05) and normal breast tissue (1.78 (0.10) p<0.001). (B) Pearson Correlation of miR-379 and Cyclin B1. A significant negative correlation was observed between Cyclin B1 and miR-379 (r=-0.31, p<0.001).