Groups of mice were euthanized 1, 3, 5, and 8 days after the placement of ligatures on the left maxillary molars. The 6-site total CEJ-ABC distance for the ligated side of each mouse was subtracted from the 6-site total CEJ-ABC distance of the contralateral unligated side of the same mouse. Panels A and B show measurements on the palatal and buccal surfaces, respectively. Data are means ± S.D. (n = 4) and negative values indicated bone loss relative to unligated baseline control. *, P < 0.05 compared to unligated baseline control.