(A) Triptolide treatment (100 nM) and miR-142-3p (5 nM) ectopic expression reduced HSPA1B (HSP70) mRNA expression (as assessed by real-time PCR) in MIA PaCa-2, Capan-1, and S2-013 cell lines following 24 h of exposure. Expression of HSPA1B (HSP70) was normalized against 18S. The bars represent mean ± SEM, n=3, *p<0.02 (t test). (B) MicroRNA-142-3p mimic (5 nM for 48 h) reduced HSP70 protein expression in MIA PaCa-2, Capan-1, and S2-013 cell lines. Expression of HSP70 was normalized against actin.