Skip to main content
. Author manuscript; available in PMC: 2014 Jul 1.
Published in final edited form as: Mol Cancer Ther. 2013 May 1;12(7):1266–1275. doi: 10.1158/1535-7163.MCT-12-1231

Figure 3. Effect of triptolide treatment or microRNA-142-3p mimic overexpression on HSPA1B (HSP70) levels.

Figure 3

(A) Triptolide treatment (100 nM) and miR-142-3p (5 nM) ectopic expression reduced HSPA1B (HSP70) mRNA expression (as assessed by real-time PCR) in MIA PaCa-2, Capan-1, and S2-013 cell lines following 24 h of exposure. Expression of HSPA1B (HSP70) was normalized against 18S. The bars represent mean ± SEM, n=3, *p<0.02 (t test). (B) MicroRNA-142-3p mimic (5 nM for 48 h) reduced HSP70 protein expression in MIA PaCa-2, Capan-1, and S2-013 cell lines. Expression of HSP70 was normalized against actin.