Table 2.
Complete metabolic response | Complete resolution of [18F]-FDG uptake within the tumor volume indistinguishable from surrounding normal tissue |
Partial metabolic response | Reduction of a minimum of 15%-25% in tumor [18F]-FDG SUV after one cycle of chemotherapy Reduction of a minimum of > 25% in tumor [18F]-FDG SUV after more than one treatment cycle |
Progressive metabolic disease | Increase in [18F]-FDG tumor SUV > 25% within the tumor region, visible increase in the extent of [18F]-FDG tumor uptake (> 20% in the longest dimension) Appearance of new [18F]-FDG uptake. |
Stable metabolic disease | Increase in tumor [18F]-FDG SUV < 25%, decrease of < 15%. No visible increase in extent of [18F]-FDG tumor uptake (< 20% in the longest dimension) |
Originated from [26], with permission. PET: Positron emission tomography; [18F]-FDG:
F-fluoro-de-oxyglucose; SUV: Standardized uptake value.