Table 3.
Clinical characteristics of patients by adherence status
| Characteristics | Good adherence, n = 2545 | Poor adherence, n = 439 | P-value | |
|---|---|---|---|---|
| Sex | Male | 1334 (52.4%) | 250 (56.9%) | P = 0.0789 |
| Female | 1211 (47.6%) | 189 (43.1%) | ||
| Age (years) | 20–29 | 1 (0.0%) | 0 (0.0%) | |
| 30–39 | 16 (0.6%) | 8 (1.8%) | ||
| 40–49 | 135 (5.3%) | 30 (6.8%) | ||
| 50–59 | 445 (17.5%) | 85 (19.4%) | ||
| 60–69 | 894 (35.1%) | 144 (32.8%) | ||
| 70–79 | 888 (34.9%) | 136 (31.0%) | ||
| 80–89 | 161 (6.3%) | 34 (7.7%) | ||
| >90 | 5 (0.2%) | 2 (0.5%) | ||
| Mean ± SD | 66.3 ± 9.9 | 65.2 ± 11.1 | P = 0.0344 | |
| Cause of liver cirrhosis | HBV | 184 (7.2%) | 33 (7.5%) | P = 0.0111 |
| HCV | 1539 (60.5%) | 216 (49.2%) | ||
| Alcohol | 393 (15.4%) | 94 (21.4%) | ||
| PBC | 59 (2.3%) | 15 (3.4%) | ||
| AIH | 52 (2.0%) | 11 (2.5%) | ||
| HBV + HCV | 13 (0.5%) | 3 (0.7%) | ||
| HBV + alcohol | 23 (0.9%) | 6 (1.4%) | ||
| HCV + alcohol | 77 (3.0%) | 15 (3.4%) | ||
| HBV + HCV + alcohol | 2 (0.1%) | 0 (0.0%) | ||
| Other | 46 (1.8%) | 11 (2.5%) | ||
| Unknown | 157 (6.2%) | 35 (8.0%) | ||
| Previous hepatic cancer | Yes | 448 (17.6%) | 56 (12.8%) | P = 0.0110 |
| No | 2078 (81.7%) | 376 (85.6%) | ||
| Unknown | 19 (0.7%) | 7 (1.6%) | ||
| Current clinical manifestations | Yes | 1321 (51.9%) | 247 (56.3%) | P = 0.1545 |
| No | 1218 (47.9%) | 192 (43.7%) | ||
| Unknown | 6 (0.2%) | 0 (0.0%) | ||
| Previous clinical manifestations | Yes | 1094 (43.0%) | 197 (44.9%) | P = 0.6969 |
| No | 1432 (56.3%) | 238 (54.2%) | ||
| Unknown | 19 (0.7%) | 4 (0.9%) | ||
| Diabetes | Yes | 457 (18.0%) | 79 (18.0%) | P = 0.9844 |
| No | 2088 (82.0%) | 360 (82.0%) | ||
| Serum albumin (g/dL) | 3.04 ± 0.36 | 3.01 ± 0.35 | P = 0.1519 | |
| Platelet (×10 000/μL) | 9.56 ± 5.85 | 10.76 ± 7.63 | P = 0.0002 | |
| AST (IU/L) | 67.2 ± 66.1 | 66.2 ± 38.1 | P = 0.7578 | |
| ALT (IU/L) | 48.4 ± 42.7 | 44.2 ± 28.7 | P = 0.0518 | |
| Serum total bilirubin (mg/dL) | 1.29 ± 0.61 | 1.33 ± 0.66 | P = 0.2430 | |
| BTR | 2.98 ± 1.42 | 2.82 ± 1.07 | P = 0.4400 | |
For categorical variables, the number of patients and percentage are shown. For continuous variables, the mean ± SD is presented. Statistical analysis was conducted by χ-test or by Student's t-test.
AIH, autoimmune hepatitis; ALT, alanine aminotransferase; AST, aspartate aminotransferase; BTR, branched-chain amino acid/tyrosine ratio; HBV, hepatitis B virus; HCV, hepatitis C virus; PBC, primary biliary cirrhosis; SD, standard deviation.