Figure 3.

Flowchart of RNAsnp program. The options “Mode 1” and “Mode 2” help to detect the SNP induced local structural changes in a given RNA sequence. The choice of the modes depends on the length of the input sequence. The option “Mode 3” helps to screen the putative structure-disruptive SNPs in an RNA sequence. This is achieved by testing the effect of all three possible substitutions at each nucleotide position. This mode facilitates an effective screening of putative structure-disruptive SNPs from transcripts or genome sequences.