Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2013 Jul 11;7:108. doi: 10.3389/fncel.2013.00108

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

Copyright © Cifelli, Palma, Roseti, Verlengia and Simonato.

This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits use, distribution and reproduction in other forums, provided the original authors and source are credited and subject to any copyright notices concerning any third-party graphics etc.

PMC Copyright notice

I_GABA rundown in oocytes injected with rat brain membranes. (A) Time course of current rundown in oocytes injected with hippocampal membranes form control rats (◦), rats killed after the first spontaneous seizure (•), and rats killed in the chronic period, 30 days after SE (□). Peak amplitudes of I_GABA were normalized to those elicited by the first GABA application (95 ± 20 nA in the control group; 115 ± 21 nA in the first seizure group; 98 ± 18 nA in the chronic group). (B) Time course of current rundown in oocytes injected with cortical membranes form control rats (◦), rats killed after the first spontaneous seizure (•), and rats killed in the chronic period, 30 days after SE (□). Peak amplitudes of I_GABA were normalized to those elicited by the first application (190 ± 25 nA in control; 230 ± 25 nA in first seizure; 201 ± 30 nA in chronic). GABA pulses were 1 mM, 10-s duration every 40 s. Data are means ± SEM (n = 12). All data sets fitted to an exponential curve.