Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2013 Jan 22;12(7):1764–1779. doi: 10.1074/mcp.M112.022947

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

© 2013 by The American Society for Biochemistry and Molecular Biology, Inc.

PMC Copyright notice

Fig. 5. — Effects of Cav-1 silencing in U2-OS cells. A, Caveolin 1 was silenced in U2-OS by transient transfection of specific siRNA. The protein expression was reduced by 70% compared with cells not transfected or transfected with unrelated siRNA (Neg siRNA). GR expression was not affected by the treatment. = Not transfected; = Neg siRNA; = Cav-1 siRNA. B, Representative pictures of GR/Cav-1 heterodimers in U2-OS transiently transfected for 48 h and 72 h with either Cav-1 siRNA or Neg siRNA. C, GR/Cav-1 dimers, expressed in average PLA signals per cell, were significantly reduced on siRNA transfection at both 48 h and 72 h. = Neg siRNA 48 h; = Cav-1 siRNA 48 h; = Neg siRNA 72 h; = Cav-1 siRNA 72 h. D, Modulation of HADH and CoxVb by Cort-BSA in U2-OS cells transfected with either Neg siRNA (), or Cav-1 siRNA (). * p < 0.05, ** p < 0.01.

Inline graphic — Effects of Cav-1 silencing in U2-OS cells. A, Caveolin 1 was silenced in U2-OS by transient transfection of specific siRNA. The protein expression was reduced by 70% compared with cells not transfected or transfected with unrelated siRNA (Neg siRNA). GR expression was not affected by the treatment. = Not transfected; = Neg siRNA; = Cav-1 siRNA. B, Representative pictures of GR/Cav-1 heterodimers in U2-OS transiently transfected for 48 h and 72 h with either Cav-1 siRNA or Neg siRNA. C, GR/Cav-1 dimers, expressed in average PLA signals per cell, were significantly reduced on siRNA transfection at both 48 h and 72 h. = Neg siRNA 48 h; = Cav-1 siRNA 48 h; = Neg siRNA 72 h; = Cav-1 siRNA 72 h. D, Modulation of HADH and CoxVb by Cort-BSA in U2-OS cells transfected with either Neg siRNA (), or Cav-1 siRNA (). * p < 0.05, ** p < 0.01.