Table II. Cort-BSA regulated proteins in CCRF-CEM cells validated by Western blot.

Protein name	Fraction	Time point	Fold change (2D-DIGE)a	Fold change (WBb)	p value
Cytochrome C oxidase subunit Vb COX5B_HUMAN	nucleus	5 min	+1.291	+1.223	0.006
Cytochrome C oxidase subunit Vb COX5B_HUMAN	cytosol	15 min	−1.373	−3.231	<0.001
3-hydroxyacyl-CoA dehydrogenase type-2 HCD2_HUMAN	cytosol	15 min	−1.296	−1.843	0.003
Prostaglandin E synthase 3 TEBP_HUMAN	nucleus	90 min	−3.869	−1.557	0.039
S-adenosylmethionine synthase isoform type-2 METK2_HUMAN	cytosol	90 min	+1.375	+1.553	0.014
Prohibitin PHB_HUMAN	nucleus	5 min	+1.239	+1.173	0.167

^a Differentially expressed protein spots were detected using the Delta2D software and accepted based on fold changes with a t-test value of p < 0.05.

^b Western Blot.