Table I. Elution times, experimental and theoretical average mass values (Da) of the proteins and peptides detected and quantified in saliva of DS subjects and controls. The term PRP-1 type includes the three entire isoforms PRP-1, PRP-2, and Pif-s, with a mass difference of 1 Da. The term PRP-3 type includes the truncated isoforms PRP-3, PRP-4, and Pif-f.
| Protein (Swiss-Prot code) | El. time (min) | Exp. av mass (Th. av mass) |
|---|---|---|
| PRP-1 type 2P (P02810) | 22.9–23.6 | 15,515 ± 2 (15,514–15,515) |
| PRP-3 type 2P (P02810) | 23.3–24.2 | 11,161 ± 1 (11,161–11,162) |
| P-C peptide (P02810) | 13.6–14.5 | 4,370.9 ± 0.4 (4,370.8) |
| Histatin 1 (P15515) | 23.3–23.8 | 4,928.2 ± 0.5 (4,928.2) |
| Histatin 3 (P15516) | 17.6–17.9 | 4,062.2 ± 0.4 (4,062.4) |
| Histatin 5 (P15516) | 14.2–14.7 | 3,036.5 ± 0.3 (3,036.3) |
| Histatin 6 (P15516) | 14.0–14.4 | 3,192.4 ± 0.3 (3,192.5) |
| Cystatin S nonP (P01036) | 37.4–38.2 | 14,186 ± 2 (14,185.8) |
| Cystatin S 1P (S1) | 37.7–38.4 | 14266 ± 2 (14,265.8) |
| Cystatin S 2P (S2) | 37.8–38.4 | 14,346 ± 2 (14,345.8) |
| Cystatin SN (P01037) | 35.8–36.4 | 14,312 ± 2 (14,313.1) |
| Cystatin SA (P09228) | 38.7–39.4 | 14,347 ± 2 (14,346.1) |
| Cystatin B dimeric form (P04080) | 33.6–34.4 | 22,362 ± 3 (22,361.2) |
| Cystatin B glutathionylated | 32.5–33.1 | 11,487 ± 2 (11,486.7) |
| Cystatin C (P01034) | 38.2–38.9 | 13,343 ± 2 (13,343.1) |
| Cystatin C methionine sulfoxide | 38.1–38.7 | 13,360 ± 2 (13,359.1) |
| Statherin 2P (P02808) | 28.9–29.5 | 5,380.0 ± 0.5 (5,379.7) |
| P-B (P02814) | 29.7–30.6 | 5,792.9 ± 0.5 (5,792.7) |
| Thymosin β4 (P62328) | 20.7–21.0 | 4,963.7 ± 0.4 (4,963.5) |
| α-defensin 1 (P59665) | 24.9–25.4 | 3,442.1 ± 0.4 (3,442.1) |
| α-defensin 2 (P59665 and P59666) | 24.9–25.4 | 3,371.0 ± 0.4 (3,371.0) |
| α-defensin 3 (P59666) | 24.9–25.4 | 3,486.1 ± 0.4 (3,486.1) |
| S100A7 (D27) (P31151a) | 37.4–38.0 | 11,367 ± 2 (11,367.8) |
| S100A8 (P05109) | 39.1–39.7 | 10,833 ± 2 (10,834.5) |
| S100A9 short 1P (P06702) | 41.3–42.0 | 12,770 ± 2 (12,769.2) |
| S100A9 short 1P methionine sulfoxide | 41.3–42.0 | 12,786 ± 2 (12,785.2) |
| S100A9 short | 41.3–42.0 | 12,690 ± 2 (12,689.2) |
| S100A9 short methionine sulfoxide | 41.3–42.0 | 12,707 ± 2 (12,705.2) |
| S100A9 long glutathionylated | 41.1–41.8 | 13,458 ± 2 (13,456.8) |
| S100A12 (P80511) | 39.5–40.2 | 10,443 ± 2 (10,443.9) |
a The Swiss-Prot code refers to the variant E27.