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. 2013 Mar 26;12(7):1844–1852. doi: 10.1074/mcp.M112.026708

Table III. Extracted ion current peak areas of other salivary proteins and peptides (mean values ± S.D. ×108) and results of the comparison between the groups.

Protein Ctrlsa (n = 18) Patientsa (n = 18) p valueb Ctrlsc (n = 18) Patientsc (n = 18) p valueb Ctrlsd p value Patientsd p value
Cyst B dimer 0.33 ± 0.43 0.23 ± 0.13 ns 0.33 ± 0.19 0.19 ± 0.12 0.01 ns ns
Cyst B glut 0.24 ± 0.28 0.51 ± 0.45 0.04 0.55 ± 0.53 0.39 ± 0.21 ns 0.03 ns
Cyst C 0.15 ± 0.23 0.28 ± 0.20 0.02 0.49 ± 0.23 0.33 ± 0.41 0.02 0.0002 ns
Cyst C sulfox 0.03 ± 0.07 0.11 ± 0.15 ns 0.03 ± 0.09 0.17 ± 0.16 0.004 ns ns
Cyst C tot* 0.18 ± 0.23 0.39 ± 0.30 0.02 0.52 ± 0.25 0.51 ± 0.45 ns 0.0002 ns
Thymosin β4 0.15 ± 0.14 0.30 ± 0.31 ns 0.43 ± 0.25 0.61 ± 0.58 ns 0.0003 0.05
α-defensin 1 0.5 ± 0.6 0.9 ± 1.0 ns 0.5 ± 0.4 2.4 ± 2.7 0.006 ns 0.03
α-defensin 2 0.4 ± 0.4 0.7 ± 0.7 ns 0.4 ± 0.3 1.6 ± 1.5 0.003 ns 0.03
α-defensin 3 0.3 ± 0.4 0.4 ± 0.5 ns 0.2 ± 0.2 0.8 ± 0.8 0.004 ns ns
S100A7 (D27) 0.07 ± 0.12 (5/18) 0.43 ± 0.55 (18/18) 0.0004 0.03 ± 0.10 (2/18) 0.28 ± 0.47 (14/18) 0.001 ns ns
S100A8 0.04 ± 0.1 (4/18) 0.14 ± 0.37 (3/18) ns 0.04 ± 0.09 (4/18) 0.17 ± 0.17 (10/18) 0.02 ns ns
S100A9 short 0.41 ± 0.49 (12/18) 0.27 ± 0.36 (11/18) ns 0.39 ± 0.44 (10/18) 0.16 ± 0.18 (12/18) 0.05 ns ns
S100A9 short sulfox 0.22 ± 0.24 (11/18) 0.17 ± 0.22 (11/18) ns 0.11 ± 0.18 (6/18) 0.21 ± 0.16 (14/18) 0.04 ns ns
S100A9 short tot* 0.63 ± 0.69 (12/18) 0.44 ± 0.50 (15/18) ns 0.50 ± 0.52 (11/18) 0.37 ± 0.30 (14/18) ns ns ns
S100A9 1P short 0.26 ± 0.34 (11/18) 0.14 ± 0.22 (10/18) ns 0.20 ± 0.27 (8/18) 0.06 ± 0.07 (8/18) 0.04 ns ns
S100A9 1P short sulfox 0.11 ± 0.18 (8/18) 0.07 ± 0.16 (6/18) ns 0.05 ± 0.11 (4/18) 0.11 ± 0.19 (10/18) ns ns ns
S100A9 1P short tot* 0.38 ± 0.47 (11/18) 0.22 ± 0.27 (12/18) ns 0.24 ± 0.34 (8/18) 0.17 ± 0.22 (11/18) ns ns ns
S100A9 long glut 0.17 ± 0.35 (6/18) 0.19 ± 0.32 (7/18) ns 0.27 ± 0.39 (8/18) 0.14 ± 0.18 (9/18) ns ns ns
S100A12 0.009 ± 0.03 (1/18) 0.04 ± 0.13 (2/18) - 0.12 ± 0.34 (2/18) 0.34 ± 0.32 (14/18) 0.002 - 0.001

a Age 10–17 yr group.

b Controls vs DS subjects.

c Age 18–50 yr group.

d Age 10–17 vs 18–50 yr group.

* Oxidized plus not oxidized forms; ns: not significant.