Table II. Detailed composition and statistical parameters of the top enriched GO terms.
| Term | Count | p valuea | Protein name | Fold Enrichmentb | Benjaminic |
|---|---|---|---|---|---|
| Anti-apoptosis (GO:0006916) | 6 | 1,7E-05 | dAnnexin A4, Glutathione S-transferase P, Thioredoxin domain-containing protein 5, 78 kDa glucose-regulated protein, Peroxiredoxin-2, Stress-70 protein, mitochondrial | 17,13 | 0,0078 |
| Negative regulation of apoptosis (GO:0043066) | 6 | 2,2E-04 | 9,97 | 0,0499 | |
| Negative regulation of programmed cell death (GO:0043069) | 6 | 2,4E-04 | 9,83 | 0,0358 | |
| Negative regulation of cell death (GO:0060548) | 6 | 2,4E-04 | 9,80 | 0,0273 | |
| Negative regulation of cellular process (GO:0048523) | 10 | 7,4E-04 | Prohibitin, Gelsolin, Proteasome subunit alpha type-1, Proteasome subunit alpha type-1, Glutathione S-transferase P, Thioredoxin domain-containing protein 5, 78 kDa glucose-regulated protein, Peroxiredoxin-2, Proteasome subunit beta type-3, Stress-70 protein, mitochondrial | 3,54 | 0,0652 |
| Hydrogen peroxide metabolic process (GO:0042743) | 3 | 7,4E-04 | Peroxiredoxin-6, Peroxiredoxin-2, Protein DJ-1 | 70,58 | 0,0553 |
| Response to stress (GO:0006950) | 10 | 8,2E-04 | Peroxiredoxin-6, Heat shock 70 kDa protein 4, Ubiquitincarboxyl-terminal hydrolaseisozyme L1, Heat shock cognate 71 kDa protein, Chlorideintracellularchannelprotein 1, Gelsolin, 78 kDa glucose-regulatedprotein, Peroxiredoxin-2, Stress-70 protein, mitochondrial, Protein DJ-1 | 3,49 | 0,0523 |
| Negative regulation of biological process (GO:0048519) | 10 | 1,4E-03 | Prohibitin, Gelsolin, Proteasome subunit alpha type-1, Annexin A4, Glutathione S-transferase P, Thioredoxin domain-containing protein 5, 78 kDa glucose-regulated protein, Peroxiredoxin-2, Proteasome subunit beta type-3, Stress-70 protein, mitochondrial | 3,25 | 0,0768 |
| Regulation of apoptosis (GO:0042981) | 7 | 1,5E-03 | *Prohibitin, Annexin A4, Glutathione S-transferase P, Thioredoxin domain-containing protein 5, 78 kDa glucose-regulated protein, Peroxiredoxin-2, Stress-70 protein, mitochondrial | 5,12 | 0,0719 |
| Regulation of programmed cell death (GO:0043067) | 7 | 1,5E-03 | 5,07 | 0,0683 | |
| Regulation of cell death (GO:0010941) | 7 | 1,6E-03 | 5,05 | 0,0634 |
a p value with a modified Fisher exact test was used to select the top enriched categories.
b Fold enrichment indicates the magnitude of enrichment.
c Benjamini multiple testing was performed to globally correct the p value controlling family-wide false discovery rate (π value ≤ 0.1).
d These proteins are the same for all GO terms of the corresponding columns.