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. 2013 Jun 25;2013:319124. doi: 10.1155/2013/319124

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Copyright © 2013 Yi-Hung Chen et al.

This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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Effects of EA at 2 Hz on GNTI- (0.3 mg/kg) induced scratching in naloxone-pretreated mice. Naloxone (s.c.; 1 mg/kg) was administered 70 min before GNTI injection, that is, 5 min before isoflurane anesthesia for EA. EA was applied to the LI4 and LI11 acupoints before GNTI administration. The number of scratches was counted for a period of 40 min after pruritogen injection. EA failed to attenuate GNTI-induced scratching behavior in naloxone-pretreated mice. Between-group comparisons for each group were performed by Student's t-test.