Table 2.
Anti-inflammatory and antiacetylcholinesterase values of scopoletin isolated from Canarium patentinervium Miq.
Compound | Anti-inflammatory assay 5-LOX, IC50 (µM) | Antiacetylcholinesterase assay, IC50 (µM) |
---|---|---|
SC | 1.76 ± 0.01 | 270.00 ± 0.02 |
NDGA | 85.23 ± 0.02 | NA |
Galantamine | NA | 2.57 ± 0.06 |
SC: isolated compound scopoletin, NDGA: nordihydroguaiaretic acid, NA: not applicable.
Data were obtained from three independent experiments, each performed in triplicates. (n = 9) and represented as mean ± SD.
IC50 < 30 µg/mL: good activity; 30 < IC50 < 80 µg/mL: moderate activity; IC50 > 80 µg/mL: poor activity.