Table 2.
HIV-1 Subtype B Codons
|
HIV-1 Subtype C Codons
|
|||||||||
---|---|---|---|---|---|---|---|---|---|---|
103 N (%) | 181 N (%) | 65 N (%) | 184 N (%) | 103 N (%) | 181 N (%) | 106 N (%) | 190 N (%) | |||
Total Specimens Tested | 49 | 49 | 72 | 72 | 92 | 92 | 90 | 90 | ||
Indeterminate in SPX OLA | 3 (6) | 2 (4) | 4 (6) | 5 (7) | 5 (5) | 8 (9) | 0 (0) | 5 (6) | ||
| ||||||||||
Total Compared in MPX vs. SPX | 46 | 47 | 68 | 67 | 87 | 84 | 90 | 85 | ||
Mutants detected by SPX | 14 (30) | 4 (9) | 0 (0) | 14 (21) | 16 (18) | 22 (26) | 8 (9) | 12 (14) | ||
Mutants detected by MPX | 14 (30) | 3 (6) | 1 (1) | 14 (21) | 14 (16) | 23 (27) | 11 (12) | 13 (15) | ||
| ||||||||||
Difference in detection (p≤)a | 1.00 | 1.00 | 1.00 | 1.00 | 0.50 | 1.00 | 0.25 | 1.00 | ||
| ||||||||||
Sensitivity of MPX | 1.00 | 0.75 | N/Ab | 1.00 | 0.88 | 0.98 | 1.00 | 1.00 | ||
Specificity of MPX | 1.00 | 1.00 | 0.99 | 1.00 | 1.00 | 1.00 | 0.96 | 0.99 |
P-values calculated by McNemar’s exact test;
Not applicable as no mutants detected by SPX-OLA.