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. 2013 Jun 18;109(1):50–59. doi: 10.1038/bjc.2013.240

Figure 5.

Figure 5

Regulation of PKB and MAPK activation by FGFR3 and miR-100. Whole cell lysates of RT4 cells transfected with scramble (Scr) or siFGFR3 siRNA (left panels) or miRNA control mimic or mimic-100 (right panels), and cultured in normoxia (N) or 0.1% O2 (H) for 24 h were probed for (A) phospho-Ser473-PKB and total PKB, and (B) phospho-Thr202/Tyr204-MAPK and total MAPK. Quantification of representative western blots are shown. (A and B) Data are representative of at least two independent experiments.