Table 1. Study population and risk of detecting any colorectal pathology at colonoscopy following a positive stool test.

	All patients		Colorectal pathology		Normal colonoscopy			Risk of colorectal pathology (multivariate analysis)
	n	%	n	%	n	%	P-value	OR	95% CI	P-value
	4188		3043		1145
Age
⩽55	877	21	565	19	312	27		1
56–64	1280	31	925	30	355	31		1.41	1.17–1.71	<0.001
⩾65	2031	49	1553	51	478	42	<0.001	1.89	1.58–2.27	<0.001
Sex
Male	2489	59	1990	65	499	44		1
Female	1699	41	1053	35	646	56	<0.001	2.49	2.16–2.86	<0.001
Deprivation category
1 (most deprived)	1506	36	1060	35	446	39		1
2	785	19	568	19	217	19		1.08	0.88–1.31	0.461
3	666	16	507	17	159	14		1.30	1.05–1.61	0.017
4	527	13	380	13	147	13		1.02	0.81–1.28	0.879
5 (least deprived)	699	17	525	17	174	15	0.017	1.21	0.98–1.49	0.080
Type of positive stool test
gFOBt	739	18	561	18	178	16		1
FIT	3449	82	2482	82	967	84	0.029	1.20	0.99–1.45	0.062
Aspirin
No	3531	84	2592	85	939	82		1
Yes	657	16	451	15	206	18	0.012	0.67	0.55–0.81	<0.001
Statin
No	3308	79	2422	80	886	77
Yes	880	21	621	20	259	23	0.117
ACE inhibitor
No	3682	88	2672	88	1010	88
Yes	506	12	371	12	165	12	0.722
⩾1 Medications
No	3088	74	2271	75	817	71
Yes	1100	26	772	25	328	29	0.032

Abbreviations: ACE=angiotensin-converting enzyme; CI=confidence interval; FIT=faecal immunochemical test; gFOBt=guaiac-based faecal occult blood test; OR=odds ratio.