Table 2. Risk of advanced neoplasia in those with colorectal pathology at colonoscopy.

	All patients		Advanced neoplasia		Non-significant pathology			Risk of advanced neoplasia (multivariate analysis)
	n	%	n	%	n	%	P-value	OR	95% CI	P-value
	3043		1704		1339
Age
⩽55	565	19	263	15	302	23		1
56–64	925	30	513	30	412	31		1.48	1.19–1.83	<0.001
⩾65	1553	51	928	55	625	47	<0.001	1.89	1.55–2.31	<0.001
Sex
Male	1990	65	1201	70	780	59		1
Female	1053	35	503	30	550	41	<0.001	1.70	1.46–1.99	<0.001
Deprivation category
1 (most deprived)	1060	35	554	33	506	38		1
2	568	19	324	19	244	18		1.16	0.94–1.43	0.16
3	507	17	278	16	228	17		1.05	0.85–1.31	0.653
4	380	13	232	14	148	11		1.33	1.04–1.70	0.021
5 (least deprived)	525	17	313	18	212	16	<0.001	1.29	1.04–1.60	0.021
Type of positive stool test
gFOBt	561	18	353	21	208	16		1
FIT	2482	82	1351	79	1131	84	<0.001	1.39	1.14–1.68	0.001
Aspirin
No	2592	85	1488	87	1104	82
Yes	451	15	216	13	235	18	<0.001
Statin
No	2422	80	1409	83	1013	76
Yes	621	20	295	17	326	24	<0.001
ACE inhibitor
No	2672	88	1524	89	1148	86
Yes	371	12	180	11	191	14	0.002
⩾1 Medications
No	2271	75	1330	78	941	70		1
Yes	772	25	374	22	398	30	<0.001	0.59	0.50–0.70	<0.001

Abbreviations: ACE=angiotensin-converting enzyme; CI=confidence interval; FIT=faecal immunochemical test; gFOBt=guaiac-based faecal occult blood test; OR=odds ratio.