. Author manuscript; available in PMC: 2013 Dec 28.

Published in final edited form as: Cancer Lett. 2012 Jul 7;325(2):175–188. doi: 10.1016/j.canlet.2012.06.014

Table 4.

Influence of primary cancer associated fibroblasts on growth and differentiation of S1 cells in 3D-collagen I matrix.

Patient-ID	Induction of growth arrest in coculture with CAF at day 9	(%) of polarized acini in coculture with CAF	(%) of polarized acini in coculture with HMF	(%) of polarized acini in monoculture
A^NF/CAF	+	65^a	4^a	28
B^NF/CAF	+	60^a	67^a	30
C^NF/CAF	−	28	54^a	24
D^NF/CAF	−	60^a	55^a	23
I^CAF	–	54^a	54^a	26
J^CAF	+	70^a	56^a	30
K^CAF	+	81^a	62^a	17
L^CAF	+	53^a	59^a	33

⁺

CAF induced growth arrest of S1 cells in coculture compared to monoculture.

⁻

CAF did not influence growth of S1 cells in coculture compared to monoculture. Bold, patients with corresponding NF samples.

Significant difference compared to monoculture (p < 0.01).