FIG. 5.

Effects of hypoxia on the levels of VHL, HIF-2α, STAT proteins, and IFN production in NDV-infected clear cell renal cell carcinoma (RCC) cells. (A) NDV infection in hypoxic condition did not drastically change the patterns of VHL, HIF-2α, and STAT proteins compared to normoxic condition. (B) Hypoxia also failed to exert any effect on the level of NDV-induced IFN-β production by the infected clear cell RCC cells. The results represent experiments performed in triplicate. C, Mock-infected control. **p<0.01, ***p<0.001.