Table 5.
Signal ratios between each strain pair
| Metabolite | wt.: adr1Δ |
wt.: cat8Δ |
wt.: adr1Δcat8Δ |
wt.: snf1Δ |
adr1Δ: cat8Δ |
adr1Δ: adr1Δcat8Δ |
adr1Δ: snf1Δ |
cat8Δ: adr1Δcat8Δ |
cat8Δ: snf1Δ |
adr1Δcat8Δ: snf1Δ |
|---|---|---|---|---|---|---|---|---|---|---|
| Glucose | 1.50 | 1.44 | 0.22 | 0.10 | 0.96 | 0.14 | 0.06 | 0.15 | 0.07 | 0.45 |
| Alanine | 0.28 | 0.26 | 0.18 | 0.18 | 0.95 | 0.66 | 0.66 | 0.69 | 0.69 | 1.00 |
| Mannitol | 0.71 | 0.32 | 0.34 | 0.82 | 0.45 | 0.47 | 1.15 | 1.06 | 2.55 | 2.42 |
| Glycine | 1.09 | 0.61 | 0.83 | 0.83 | 0.56 | 0.77 | 0.77 | 1.37 | 1.37 | 1.00 |
| 2-Monostearin | 0.68 | 0.76 | 1.22 | 0.52 | 1.10 | 1.78 | 0.76 | 1.61 | 0.68 | 0.42 |
| Stearic acid | 0.90 | 0.80 | 0.95 | 0.66 | 0.90 | 1.06 | 0.73 | 1.18 | 0.82 | 0.69 |
| Valine | 0.21 | 0.78 | 0.49 | 0.20 | 3.73 | 2.33 | 0.93 | 0.62 | 0.25 | 0.40 |
| Benzoic acid | 0.97 | 0.88 | 1.05 | 0.69 | 0.91 | 1.08 | 0.72 | 1.19 | 0.79 | 0.66 |
| Lysine | 1.03 | 0.97 | 0.88 | 0.71 | 0.94 | 0.85 | 0.68 | 0.91 | 0.73 | 0.80 |
| 3-OH butyric | 0.76 | 0.42 | 0.50 | 1.63 | 0.55 | 0.66 | 2.14 | 1.21 | 3.91 | 3.24 |
| Glycerol | 2.05 | 1.95 | 0.38 | 1.02 | 0.95 | 0.19 | 0.50 | 0.20 | 0.52 | 2.65 |
| Glucosamine | 0.98 | 1.03 | 1.10 | 0.74 | 1.04 | 1.12 | 0.75 | 1.08 | 0.72 | 0.67 |
| Glycerate 3 phosphate |
1.05 | 10.59 | 20.53 | 0.49 | 10.12 | 19.62 | 0.47 | 1.94 | 0.05 | 0.02 |
| CoA fragment | 0.91 | 0.95 | 0.89 | 0.85 | 1.04 | 0.97 | 0.93 | 0.93 | 0.90 | 0.96 |
| Pyruvate | 1.03 | 1.36 | 1.06 | 0.78 | 1.32 | 1.02 | 0.75 | 0.78 | 0.57 | 0.74 |
| CMP | 0.97 | 0.69 | 0.56 | 1.56 | 0.71 | 0.57 | 1.60 | 0.81 | 2.25 | 2.79 |
| NADP | 1.28 | 1.39 | 1.23 | 0.88 | 1.09 | 0.96 | 0.69 | 0.88 | 0.63 | 0.72 |
| FAD | 0.84 | 0.84 | 0.81 | 0.98 | 1.01 | 0.97 | 1.17 | 0.96 | 1.16 | 1.21 |
| Deoxyadenosine | 1.13 | 1.08 | 1.14 | 0.99 | 0.95 | 1.00 | 0.88 | 1.06 | 0.92 | 0.87 |
| Tyrosine | 1.09 | 0.60 | 0.66 | 3.09 | 0.55 | 0.61 | 2.85 | 1.10 | 5.18 | 4.70 |
| Glycolic | 0.97 | 1.04 | 0.97 | 0.97 | 1.07 | 1.01 | 1.00 | 0.94 | 0.93 | 0.99 |
| Uracil | 0.89 | 0.99 | 0.99 | 0.94 | 1.12 | 1.12 | 1.06 | 1.00 | 0.95 | 0.95 |
| TPP | 1.01 | 1.24 | 1.23 | 0.96 | 1.23 | 1.22 | 0.95 | 1.00 | 0.77 | 0.78 |
| 3-OH propionic | 1.12 | 1.09 | 1.16 | 1.16 | 0.98 | 1.04 | 1.04 | 1.06 | 1.06 | 1.00 |
| Threonine | 1.22 | 1.06 | 0.98 | 1.55 | 0.87 | 0.80 | 1.27 | 0.92 | 1.46 | 1.58 |
| FMN | 1.04 | 1.09 | 1.28 | 1.22 | 1.05 | 1.23 | 1.18 | 1.18 | 1.12 | 0.95 |
| SAM | 1.32 | 1.19 | 1.36 | 1.39 | 0.90 | 1.03 | 1.05 | 1.14 | 1.16 | 1.02 |
| Ornithine | 1.07 | 1.22 | 1.43 | 1.17 | 1.15 | 1.34 | 1.09 | 1.17 | 0.95 | 0.82 |
| Isoleucine | 1.04 | 0.94 | 0.81 | 1.86 | 0.90 | 0.78 | 1.79 | 0.87 | 1.99 | 2.28 |
| Glycerol 3 phosphate |
1.20 | 0.91 | 0.67 | 2.96 | 0.76 | 0.56 | 2.47 | 0.73 | 3.24 | 4.44 |
| Orotic | 1.05 | 1.06 | 0.84 | 1.76 | 1.01 | 0.80 | 1.70 | 0.79 | 1.68 | 2.12 |
| Cystathionine | 1.18 | 0.94 | 0.79 | 3.04 | 0.79 | 0.67 | 2.57 | 0.85 | 3.25 | 3.83 |
| Adenine | 1.17 | 1.30 | 0.89 | 1.76 | 1.11 | 0.76 | 1.50 | 0.69 | 1.36 | 1.98 |
| SAH | 1.30 | 1.08 | 10.8 | 2.45 | 0.83 | 0.83 | 1.88 | 1.00 | 2.28 | 2.28 |
| Leucine | 1.13 | 1.11 | 0.83 | 2.51 | 0.98 | 0.74 | 2.23 | 0.76 | 2.27 | 3.01 |
| Arabinose | 1.03 | 1.27 | 1.18 | 1.81 | 1.23 | 1.15 | 1.75 | 0.93 | 1.42 | 1.53 |
| ADP | 0.99 | 1.34 | 1.23 | 1.63 | 1.35 | 1.24 | 1.64 | 0.92 | 1.22 | 1.33 |
| Threonine | 1.31 | 1.48 | 1.29 | 1.93 | 1.13 | 0.98 | 1.47 | 0.88 | 1.31 | 1.49 |
| Phenylalanine | 1.16 | 1.29 | 0.88 | 3.32 | 1.11 | 0.76 | 2.86 | 0.69 | 2.58 | 3.76 |
| Adenosine, 5′S methyl 5′thio-N- |
1.02 | 1.47 | 1.37 | 2.01 | 1.45 | 1.35 | 1.97 | 0.93 | 1.36 | 1.46 |
| Lactic acid | 2.01 | 2.22 | 1.35 | 2.96 | 1.10 | 0.67 | 1.47 | 0.61 | 1.33 | 2.19 |
| G1P | 1.12 | 1.94 | 2.72 | 2.21 | 1.74 | 2.43 | 1.98 | 1.40 | 1.14 | 0.18 |
| Methionine sulfoxide |
1.52 | 2.03 | 1.04 | 8.45 | 1.34 | 0.69 | 5.56 | 0.51 | 4.17 | 8.11 |
| Methionine | 1.25 | 2.72 | 1.27 | 3.26 | 2.18 | 1.01 | 2.60 | 0.47 | 1.20 | 2.57 |
| Tryptophan | 1.29 | 2.04 | 1.26 | 5.59 | 1.59 | 0.98 | 4.35 | 0.62 | 2.74 | 4.42 |
| Citrate | 1.18 | 2.04 | 2.03 | 3.71 | 1.73 | 1.72 | 3.14 | 1.00 | 1.82 | 1.83 |
| Serine | 1.18 | 2.02 | 1.19 | 8.89 | 1.72 | 1.01 | 7.55 | 0.59 | 4.39 | 7.44 |
| UDP | 1.05 | 3.42 | 3.43 | 2.25 | 3.27 | 3.27 | 2.15 | 1.00 | 0.66 | 0.66 |
| Arginine | 1.45 | 5.67 | 0.91 | 28.84 | 3.90 | 0.62 | 19.85 | 0.16 | 5.08 | 31.82 |
| UDP-N acetylglucosamine |
1.08 | 3.27 | 4.26 | 2.68 | 3.02 | 3.93 | 2.47 | 1.30 | 0.82 | 0.63 |
| Glutamate, 5-oxoproline |
0.94 | 2.41 | 2.13 | 5.21 | 2.57 | 2.26 | 5.54 | 0.88 | 2.16 | 2.45 |
| Asparagine | 1.05 | 4.16 | 2.24 | 3.47 | 3.95 | 2.12 | 3.29 | 0.54 | 0.83 | 1.55 |
| Glutamic acid |
0.97 | 2.66 | 1.97 | 6.51 | 2.74 | 2.02 | 6.69 | 0.74 | 2.44 | 3.31 |
| UDP/G1P | 1.10 | 3.40 | 3.05 | 3.72 | 3.08 | 2.76 | 3.37 | 0.90 | 1.09 | 1.22 |
| Proline | 0.93 | 2.78 | 2.13 | 6.71 | 2.99 | 2.29 | 7.21 | 0.77 | 2.42 | 3.16 |
| UDP-glucose | 1.07 | 4.10 | 5.50 | 3.89 | 3.82 | 5.12 | 3.63 | 1.34 | 0.95 | 0.71 |
| Aspartic acid | 1.25 | 4.92 | 2.69 | 6.06 | 3.93 | 2.15 | 4.84 | 0.55 | 1.23 | 2.25 |
| Asparagine | 0.97 | 5.38 | 2.03 | 13.54 | 5.52 | 2.08 | 13.90 | 0.38 | 2.52 | 6.68 |
| Alpha-ketoglutaric acid | 0.89 | 5.02 | 6.08 | 4.58 | 5.61 | 6.80 | 5.12 | 1.21 | 0.91 | 0.75 |
| G6P | 1.40 | 8.72 | 7.48 | 7.63 | 6.23 | 5.34 | 5.45 | 0.86 | 0.87 | 1.02 |
| Glutamine | 0.90 | 14.03 | 4.81 | 32.05 | 15.54 | 5.33 | 36.50 | 0.34 | 2.28 | 6.66 |
| Succinate | 1.17 | 12.98 | 11.62 | 21.82 | 11.10 | 9.94 | 18.66 | 0.90 | 1.68 | 1.88 |
| Malate | 1.00 | 15.89 | 14.70 | 19.67 | 15.90 | 14.70 | 19.68 | 0.92 | 1.24 | 1.34 |
| Fumarate | 1.35 | 10.94 | 16.14 | 50.73 | 8.11 | 11.96 | 37.59 | 1.48 | 4.64 | 3.14 |
| Trehalose | 1.39 | 12.09 | 13.31 | 141.29 | 8.66 | 9.54 | 101.28 | 1.10 | 11.69 | 10.62 |
A signal ratio is provided for each pair relative to the column headings (A:B=A/B). For example, in the top left cell, there is 1.50 times more glucose in wild type than in adr1. The statistical significance of these ratios can be determined in Table 4