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. Author manuscript; available in PMC: 2013 Jul 11.
Published in final edited form as: Exp Eye Res. 2011 May 12;93(4):371–381. doi: 10.1016/j.exer.2011.04.011

Table 2.

Thermodynamic Parameters for Equilibrium Unfolding/Refolding and Kinetic Unfolding of L5S HγD-Crys

Equilibrium Unfolding
t1 t2 m1 m2 ΔG1 ΔG2 ΔΔG
100 mM NaPia 0.7 ± 0.1 2.9 ± 0.1 4.4 ± 0.2 3.1 ± 0.2 3.1 ± 0.2 8.9 ± 0.4 N/A
250 mM NaCit 1.0 ± 0.1 3.4 ± 0.1 5.8 ± 1.6 2.8 ± 0.3 5.6 ± 1.7 9.6 ± 1.1 2.9
Kinetic Unfolding
k1 t1
100 mM NaPi 0.68 ± 0.08 1.5 ± 0.2
250 mM NaCit 0.53 ± 0.01 1.9 ± 0.1