Figure 12.
Arteriolar tortuosity index of retinas from eyes injected with either 50 ng VEGF antibody (VEGFab) or 50 ng control IgG at p12 and analyzed at p14. (A) The tortuosity index was significantly reduced in eyes injected with 50 ng VEGFab compared with that in IgG-injected eyes (ANOVA *P = 0.004, post hoc protected t-test). (B) Examples of retinas from eyes injected with 50 ng VEGFab and (C) 50 ng control IgG resulted in tortuosity indices of 1.03 ±0.007 and 1.11 ±0.04, respectively. (re-plotted from Investigative Ophthalmology and Visual Sciences; 2008 Jul;49(7):3107–14).
