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. Author manuscript; available in PMC: 2013 Jul 11.
Published in final edited form as: Doc Ophthalmol. 2009 Jul 29;120(1):25–39. doi: 10.1007/s10633-009-9181-x

Figure 13.

Figure 13

Left: Artist diagram showing long axis of vessel and cleavage plane angle. An angle of 90 degrees predicts elongation of the vessel based on the migration of the dividing endothelial cells whereas an angle of 180 degrees predicts dilation. An irregular group of cleavage plane angles may be seen in disordered angiogenesis. Right: Lectin stained flat mounted vessel with cleavage planes drawn in to demonstrate how technique is performed.