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. Author manuscript; available in PMC: 2013 Jul 11.

Published in final edited form as: Doc Ophthalmol. 2009 Jul 29;120(1):25–39. doi: 10.1007/s10633-009-9181-x

a. Phosphorylated p47-phox, a subunit of activated NADPH oxidase, is increased in the 50/10 OIR+SO model compared to 50/10 OIR model.

b. Inhibition of ROS from activated NADPH oxidase using apocynin reduces area of intravitreous neovascularization in the 50/10 OIR+SO model. (re-plotted from Investigative Ophthalmology and Visual Sciences, 2008; 49(4);1591–1598.)

a. Phosphorylated p47-phox, a subunit of activated NADPH oxidase, is increased in the 50/10 OIR+SO model compared to 50/10 OIR model.

b. Inhibition of ROS from activated NADPH oxidase using apocynin reduces area of intravitreous neovascularization in the 50/10 OIR+SO model. (re-plotted from Investigative Ophthalmology and Visual Sciences, 2008; 49(4);1591–1598.)