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A. Lectin-stained retinal flat mount of pup in 50/10 OIR model at postnatal day (p)14 after 7 cycles of oxygen fluctuations between 50% and 10% inspired oxygen showing peripheral avascular retina, similar to that in zone II ROP.
B. At p18, after return to room air for 4 additional days, intravitreous neovascularization develops at the junction of vascular and peripheral avascular retina.
