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Mean (n = 3) rates of oxycodone (OC) use and noroxycodone (NO) and oxymorphone (OM) formation (A), and NO (B) and OM (C) formation in individual HLM. HLM at 0.5 mg prot/mL was incubated with 100 ng/mL oxycodone; each time point per HLM was performed in duplicate.
