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Oxycodone (OC) depletion and noroxycodone (NO) and oxymorphone (OM) formation in a panel of cDNA-expressed human liver CYPs incubated for a set time with 30 ng/mL oxycodone (A); OC depletion and NO and OM formation over time in CYP2C18, 2D6 and 3A4 incubated with 30 ng/mL oxycodone (B). Each result is from duplicate incubations.
