Figure 6.

Interactive network of the 11 genes shared among the top 1,000 SNPs of each population. The 11 genes are CDH13, CSMD1, CTNNA2, NPAS3, PDE1C, PDE4D, PTPRD, RBFOX1, ROBO2, RYR2, and SEMA5A. Genes with red nodes represent hub genes in our analysis; others are generated through the network analysis from Ingenuity Pathways Knowledge Base. Edges are displayed with labels that describe the nature of the relationship between the nodes. All edges are supported by at least one reference from the literature or from canonical information stored in the Ingenuity Pathways Knowledge Base. The lines between genes represent known interactions, with solid lines representing direct interactions and dashed lines representing indirect interactions. Nodes are displayed using various shapes that represent the functional class of the gene product.