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. 2013 Jul 15;24(14):2186–2200. doi: 10.1091/mbc.E12-10-0737

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© 2013 Flusberg et al. This article is distributed by The American Society for Cell Biology under license from the author(s). Two months after publication it is available to the public under an Attribution–Noncommercial–Share Alike 3.0 Unported Creative Commons License (http://creativecommons.org/licenses/by-nc-sa/3.0).

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FIGURE 2: — TRAIL survivors are cross-resistant to Fas agonists and vice versa, but are sensitive to inducers of intrinsic cell death. (A–C) Cell viability assay showing the sensitivity of control cells vs. TRAIL, Anti-FasR, or staurosporine survivors (day 1) to a subsequent 6-h treatment with the indicated doses of Anti-FasR (A), staurosporine (B), or TRAIL (C). (D) Sensitivity of control vs. TRAIL-survivor cells (day 1) to an 18-h treatment with the indicated doses of doxorubicin.