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. 2013 Jul 15;24(14):2238–2247. doi: 10.1091/mbc.E13-03-0156

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© 2013 Vitriol et al. This article is distributed by The American Society for Cell Biology under license from the author(s). Two months after publication it is available to the public under an Attribution–Noncommercial–Share Alike 3.0 Unported Creative Commons License (http://creativecommons.org/licenses/by-nc-sa/3.0).

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FIGURE 7: — Live-cell superresolution imaging of actin demonstrates an increase in lamellipodial F-actin after CALI of cofilin. (A) Representative images of Lifeact-EGFP before and after CALI of cofilin-KR in cofilin-KD cells taken with 3D-SIM imaging. (B) Close-up images of the region indicated by the red box in A. After CALI, the lamellipodia significantly extended inward and displayed numerous long filaments interspersed throughout. Scale bars, 5 μm.