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. 2013 Jul 9;12:101. doi: 10.1186/1475-2840-12-101

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Copyright © 2013 Cox and Marsh; licensee BioMed Central Ltd.

This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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Effects of diabetes and 4 weeks of exercise on the interaction of mSin3A/HDAC1/2 with OGT and O-GlcNAc in type 2 diabetic db/db and non-diabetic C57BL/6J hearts. (A) Immunoblot and (B-F) blot quantification showing the O-GlcNAc modification and the association of the mSin3A/REST/HDAC1/2 complex with OGT in C57BL/6J (C57) and db/db (db) mice who were treadmill exercise trained (Ex) or sedentary (Sed) for 4 weeks. N = 6 per group. * Significant effect of genotype within exercise group, P < 0.05. # Significant effect of exercise within a genotype group, P < 0.05. ‡ Significant main effect of exercise, P < 0.05.