Table 3. Interaction between loci that control splenomegaly after 43 weeks of L. tropica infection.
P = 0.00026 | Corrected P = 0.010 | % of explained variance = 9.05 | ||||||
D2Mit257 (Ltr2) | ||||||||
CC | CS | SS | ||||||
D3Mit11 | CC | 3.98 | 1.41±0.09 | 4.58 | 1.55±0.06 | 5.24 | 1.69±0.08 | |
( Ltr3 ) | (n = 14) | (n = 33) | (n = 17) | |||||
CS | 4.51 | 1.54±0.06 | 4.35 | 1.50±0.04 | 5.32 | 1.71±0.08 | ||
(n = 36) | (n = 63) | (n = 19) | ||||||
SS | 4.37 | 1.50±0.10 | 5.23 | 1.69±0.06 | 3.12 | 1.16±0.13 | ||
(n = 13) | (n = 31) | (n = 7) |
Means, SE and P values for splenomegaly were calculated by analysis of variance. Normal distribution was obtained for splenomegaly (spleen-to-body weight ratio×1000) by raising values to the power of 0.00002. The numbers in bold give the average non-transformed values. Only P values significant after correction for genome-wide significance are given. Number of tested mice is shown in brackets. C and S indicate the presence of BALB/c and STS allele, respectively.