Figure 5. Down regulation of PbGP43 correlated with reduced fungal burden in lungs of infected BALB/c mice.

Graphs represent CFU (expressed as log₁₀ values) recovered from lung homogenates 50 days after intratracheal infection with 1×10⁶ viable yeasts of PbWt, PbEV or PbGP43 aRNA1. Eight mice per fungal strain were used and error bars indicate standard deviations. P values (**p<0.0071, ***p<0.0002) represent significant differences in comparison with the PbWt or PbEV.