Table 2. Cytokine levels in lung homogenates of BALB/c mice infected i.t. with P. brasiliensis PbWT, PbEV and PbGP43 aRNA1 yeast cells after 7 weeks of infection.
Cytokinespg/ml | TNF-α | IFN-γ | IL-12 | IL-10 | IL-6 |
PbWt | 54.6±12.1 | 17.8±2.1 | 2319.0±438 | 330.6±12.5 | 133.5±8.9 |
PbEV | 48.5±24.8 | 14.8±4.4 | 1934.8±262 | 283.3±9.8 | 119.8±7.6 |
PbGP43aRNA1 | 87.5±19.1 | 21.3±6.2 | 1730.9±250.4 | 177.0±13.2* | 98.3±7.01* |
Statistically significant difference (P<0.05) relative to mice infected with PbWT or PbEV.