Figure 1. Four patterns of response to electrical stimulation in wild-type retinal INL cells.

Representative averaged traces from a variety of INL cell types in the wild-type retina, black traces: A, Slow depolarization classified by the peak of the response occurring >10ms after stimulus onset. B, Oscillation, positive and negative responses continuing >10ms after stimulus onset. C, Fast depolarization (<10ms after stimulus onset). D, Fast hyperpolarization (<10ms after stimulus onset), dotted line depicts baseline. Grey traces: representative averaged traces (not necessarily from the same cell) after treatment with the synaptic blocker CdCl₂ (0.5mM), response amplitudes were greatly reduced and the oscillation response completely blocked. Note different scales for fast responses.