Figure 2. Four patterns of response to electrical stimulation in rd/rd retinal INL cells.

Representative averaged traces from a variety of INL cell types in the rd/rd retina, black traces: A, Slow depolarization (peak occurring >10ms after stimulus onset). B, Oscillation, positive and negative responses continuing >10ms after stimulus onset. C, Fast depolarization (<10ms after stimulus onset). D, Fast hyperpolarization (<10ms after stimulus onset). Grey traces: representative averaged traces (not necessarily from the same cell) after treatment with the synaptic blocker CdCl₂ (0.5mM), response amplitudes were not significantly altered but slow depolarization and oscillation responses were completely blocked. Note different scales for fast responses.