Skip to main content
. Author manuscript; available in PMC: 2014 Aug 1.
Published in final edited form as: Biochem Genet. 2013 Mar 17;51(0):524–529. doi: 10.1007/s10528-013-9583-z

Fig. 1.

Fig. 1

Simplified family pedigrees (left) and audiograms (right) for three deaf individuals with homozygous GJB2 mutations. The parents of each individual are first cousins. In the audiograms, hearing thresholds of the right ear are marked by circles, left ear by crosses. Study participant SIHT.13 (top), in whom the c.71 G→A mutation (p.W24X) was observed, had a profound hearing loss. Participant SIHT.28 (center), in whom the transversion mutation c.104 T→G (p.I35S) was observed, had a severe to profound hearing loss. Participant SIHT.63 (bottom), in whom a single nucleotide deletion (c.35delG) was observed, had a moderate to severe hearing loss.