Table 1.

Univariate analysis comparing maternal variables between cases with periventricular white matter injury on head ultrasound at 6 weeks of life and controls matched by gestational age with normal head ultrasounds

	Cases N=21	Controls N=42	P value
Maternal Age (years)	27.8±7.2	28.1±7.4	0.86
Parity (median)	1	1	0.65
Race			0.83
White	6 (28.6%)	9 (21.4%)
Black	13 (61.9%)	30 (71.4%)
Other	2 (9.5%)	3 (7.1%)
Cesarean	13 (61.9%)	26 (61.9%)	1.0
Twins	4 (19.0%)	5 (11.9%)	0.49
Preterm labor	14 (66.7%)	19 (45.2%)	0.16
PPROMa	5 (23.8%)	14 (33.3%)	0.49
Preeclampsia	2 (9.5%)	15 (35.7%)	0.03*
Antenatal Magnesium	8 (38.1%)	22 (52.4%)	0.29
IUGRb	0	7 (16.7%)	0.09
Oligohydramnios	1 (4.8%)	5 (11.9%)	0.24
Steroid administration	12 (57.1%)	35 (83.3%)	0.03*
Abruption	5 (23.8%)	4 (9.5%)	0.15
Nonreassuring fetal heart rate tracing	6 (28.6%)	5 (11.9%)	0.11
Clinical chorioamnionitis	1 (4.8%)	11 (26.2%)	0.08
Histologic chorioamnionitis	3 (14.3%)	16 (38.1%)	0.053
Histologic funisitis	2 (9.5%)	8 (19.0%)	0.21
Histologic placental infarct	1 (4.8%)	5 (11.9%)	0.73

^*indicates p<0.05

^aPPROM = preterm premature rupture of membranes

^bIUGR = intrauterine growth restriction