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. Author manuscript; available in PMC: 2014 May 1.
Published in final edited form as: Pediatr Infect Dis J. 2013 May;32(5):e217–e226. doi: 10.1097/INF.0b013e3182865409

Table 2.

Characteristics of the 95 studies that met inclusion criteria

Reports included 95
Countries and territories included 57
Year range during which data were collected 1952-2010
Total pediatric patients with drug-susceptibility testing (DST) results for at least isoniazid and rifampicin 8351
    New (%) 2980 (36)
    Previously treated (%) 226 (3)
    Unknown/unspecified treatment history (%) 5145 (62)
Number of reports (%) Number of pediatric patients (%)
Number of pediatric patients with DST results per report
    0-10 28 (29) 114 (1)
    11-50 35 (37) 749 (9)
    51-100 14 (15) 1128 (14)
    101-500 15 (16) 2802 (34)
    >500 (max. 2,456) 3 (3) 3558 (43)
Source of data used in report
    Reported surveillance data 20 (21) 3908 (47)
    Hospital records 48 (51) 2736 (33)
    Laboratory records 9 (9) 802 (10)
    Representative population sample 9 (9) 270 (3)
    Other or not specified 4 (4) 542 (6)
Reports with restricted study populations* 32 (34) 720 (9)
*

Includes study populations restricted to patients with pulmonary TB, smear positive TB, extrapulmonary TB, TB meningitis, TB pleurisy, or HIV coinfection; patients with no previous treatment, patients who failed treatment, or patients on DOTS treatment; patients with HIV-infected family member(s); refugees; and/or contacts of source cases with DST results.